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[PDF] Novel Aspects in Acute Lymphoblastic Leukemia

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PDF Novel Aspects in Acute Lymphoblastic Leukemia


Author: Stefan Faderl | Publisher: InTeOpP | Category: Medicine | Language: English | Page: 268 | ISBN: ec547a2e4b8c40b9ae208e461c097cdb |

Description: This book provides a review of every one of its many facets, the chapters from many investigators from around the world cover a number of relevant topics: aspects of the epidemiology of ALL in Hispanics, ophthalmologic manifestations of ALL, overviews of current therapy and drug-resistance mechanisms, novel biological pathways and targets, new drugs in development, and long-term consequences of CNS prophylaxis and therapy. Contents Preface Part 1 Epidemiology 1 Childhood Acute Leukemias in Hispanic Population: Differences by Age Peak and Immunophenotype Part 2 NK Cell Leukemia 2 Natural Killer Cell Leukemia: Diagnosis, Pathogenesis and Treatment Part 3 Clinical Manifestations of Acute Lymphoblastic Leukemia 3 Ophthalmological Manifestations in Acute Lymphoblastic Leukemia 4 Acute Lymphoblastic Leukemia: What Have We Learned About the Effects of This Disease and Its Treatment on the Nervous System? Part 4 Therapy of Acute Lymphoblastic Leukemia 5 Treatment of Pediatric Acute Lymphoblastic Leukemia and Recent Advances 6 Cellular Therapy of ALL Part 5 Resistance to Therapy 7 Multidrug Resistance Mechanism of Acute Lymphoblastic Leukemia Part 6 Pathophysiology and Novel Targets 8 Novel Therapeutic Targets in ALL Therapy 9 Aberrant Proliferative and Apoptotic Pathways in Acute Lymphoblastic Leukemia (ALL): Molecular Therapies to Overcome Chemo-Resistance 10 The Role of PAX5 in ALL 11 p53 as a Therapeutic Target in T-ALL

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